EyeWorld Korea December 2025 Issue

SUPPLEMENT

Improving Patient Outcomes with Next-Generation IOLs and a Solution for KLEx

Supplement to EyeWorld Asia-Pacific December 2025

Prof. Bissen-Miyajima also selects patients who would like to have good vision from distance to near and who have less concern about halos. Patients must accept that they may experience halos before being implanted with Odyssey™, but if they are concerned with dysphotopsia, Prof. Bissen-Miyajima will choose an EDOF lens instead. Finally, she will choose patients who do not have ocular comorbidities which may influ ence postoperative visual acuity or contrast sensitivity. In Prof. Bissen-Miyajima’s retrospective study 2 and what will be the first published study on Odyssey™, 50 eyes of 25 patients with no ocular dis eases influencing visual function and no history of intraocular and corneal surgeries were bilaterally implanted with the Odyssey™ IOL. The results of Prof. Bissen-Miyajima’s study showed that both uncorrected and distance-corrected visual acuities (DCVA) achieved 20/20 or better at 5 m, 60 cm, and 40 cm. At 30 cm, both uncorrected visual acuity and DCVA “decreased a little bit, but this vision is good enough for patients,” Prof. Bissen-Miyajima stated. Furthermore, binocular DCVA of 20/20 or better was maintained between +0.5 D and -2.0 D of defocus, and con trast sensitivity was within normal range in all spatial frequencies. Finally, 84% and 76% of patients reported none or minimal glare and starbursts, respectively. Though there are many competitors on the market, the TECNIS platform provides improved contrast sensitivity and clarity along with good stabilization in the bag with the lens’ haptic design. Regarding postoperative refraction values with the Odyssey™ IOL, there was a difference between subjective and objective refraction. Using the autorefractometer for objective refraction values resulted in overminus values for spherical power and spherical equivalent. “When you measure corrected visual acuity, please be careful not to use the refractive value of the autorefractor as is,” Dr. Bissen-Miyajima advised. The PureSee™ and Odyssey™ lenses have greatly improved the outcomes for night vision, contrast sensitivity, and overall patient satisfaction,” Dr. Sachdev said. “ On the TECNIS platform, the PureSee™ IOL is a refractive design based on a continuous change in power, which is created by a smooth change in elevation on the posterior surface of the IOL. ”

Prominent leaders in cataract and refractive surgery gathered at the Johnson & Johnson lunch symposium held at the 37th APACRS Ahmedabad on Friday, 22 August 2025 to discuss new intraocular lens (IOL) technology and an advanced laser vision correction solution.

Real-world Experiences with Various Next-generation IOLs

With a long and strong history of excellent outcomes, the TECNIS TM IOL platform has produced many go-to lenses for cataract surgeons across the globe with millions of TECNIS TM 1-piece IOLs having already been im planted. The TECNIS Eyhance TM IOL was then developed after the 1-piece IOL and is a gold standard, advanced monofocal lens that comes on both a toric and a monofocal plus platform. Then came the full range of vision lens: the TECNIS PureSee™ IOL. The PureSee™ IOL is a pure extended depth of focus (EDOF) lens that is able to minimize photic phenomena. “The key principle defining an EDOF IOL is a single, contiguous, elongated focal point that enhances depth of focus,” said Tim Roberts, MBBS, MMed, FRANZCO, GAICD (Australia). “An ideal EDOF IOL provides a sharp focus over a wide range, from Plano to -1.5 D, thus giving the patient excellent distance and intermediate vision.” On the TECNIS TM platform, the PureSee™ IOL is a refractive design based on a continuous change in power, which is created by a smooth change in elevation on the posterior surface of the IOL. Because the posterior curvature change is gentle, the lens should not induce any unwanted dysphotopsia such as glares and halos. In an international proof-of-concept study conducted between 2020 and 2022, Prof. Roberts examined the visual performance and safety of bilat erally implanting PureSee™ in 60 patients compared to the performance and safety of a standard monofocal lens in 131 patients. ¹ The results showed that best corrected distant visual acuity (BCDVA) was comparable in both groups. However, distance-corrected intermediate visual acuity (DCIVA) in eyes implanted with PureSee™ showed two lines of improve ment with 82% of PureSee™ eyes achieving 0.20 logMAR (6/9) or better compared to 19% of eyes implanted with the standard monofocal lens. By conducting routine biometry and choosing a “first minus” IOL power, Prof. Roberts has seen patients attaining minimal or no dysphotopsias. With the TECNIS TM platform continually developing, the TECNIS Odyssey™ IOL was recently launched and is a next-generation presbyopia-correcting IOL (PC IOL) with strong clinical outcomes. The Odyssey™ IOL consists of a new freeform diffractive profile that enhances the tolerance to refractive error with its smooth defocus curve. The Odyssey™ IOL optimizes its dysphotopsia profile by delivering a lower intensity as the distance of the halo center increases. Being a part of the TECNIS platform provides the Odyssey™ IOL even more advantages including better contrast with a low amount of chromatic aberration, lower rates of glistening and posterior capsule opacification, and better rotational stability with its squared and frosted haptic design. For Hiroko Bissen-Miyajima, MD, PhD (Japan), patient selection for the Odyssey™ IOL depends on a few factors. She will select patients who desire spectacle independence and who are ready to pay the extra cost. “In Japan, patients need to pay out-of-pocket for PC IOLs,” she said.

The PureSee™ IOL provides a high distance image quality comparable to a monofocal IOL at 3-month follow-up. Credit: Vision Eye Institute

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EyeWorld Asia-Pacific | December 2025